Akyeame is made up of Okyeame Quame (Quame Nsiah Appau) and Okyeame Quophi (Daniel Quophi Amoateng). They are both solo artistes now. Quame was a DJ at Fox FM, 97.9 and Quophi at Luv FM, 99.5 (both in Kumasi) during a hiatus when they concentrated on other careers than music. Okyeame Quophi is now producing other artistes and making music videos through his Emklan entertainment company while Okyeame Quame is helping his brothers - (Bradez) Kunta Kinte and Stone - enter the hiplife game.

They are famous for their hit, Mesan aba, which was the first hiplife song to win a major Ghana music award. They are two of the most respected rappers in Ghana.

Some of their popular songs include Bra yen tina, Adonko, Sankofa, Ene yebeda okyena, Brebre, Sick with love, Obanyansafo, Damirifa due, Di asa, Asa a aba so, All I got, Akuaba (remix with Kojo Antwi), etc.