Henry De-Mensah is known as the man with the silky voice. Nana Quame as he is affectionately called is a highlife musician in Ghana.

He had his primary education in Accra and went on to Nungua Presec. He later banded with Blackface who was a rapper and they began recording. They recorded cuts like Obi agye wo and Okwantuni.

He was discovered by Kojo Antwi when he won the R&B King of the Year Award at His Majesty Nite Club in 1996. He then went to feature in many hit tracks like Philomena with Tic Tac and Obrafour, Mesan aba with Akyeame and Yoggi Doggi, etc.

His debut album was Yate under the watch of Kojo Antwi's Family Spirit Records. He then recorded the Odo Shock album through Slip Music in 2000 which was more successful.

His third album, Fakye, came out in 2001 and had a chart topper called Menko meda featuring Sass Squad. His biggest hit to date was Atia Donko on the fourth album which was self-tilted which also featured Yoggi Doggi in 2003.

His fifth album, Solja, came out in 2005 and after a long break, Power, another album was released in 2007.

Some of his songs include Asem sebe, Auntie Adiza, Twe ma me, Anigiye, Yebesa, Power, Asew konofo, Solja Alafia, Koye me ho adee, Waa ware mea, Emmaa no titi me, Eno Abena, etc